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CAS Number: 21679-14-1

Chemical Name:

Fludarabine

Synonims:

9-bata-D-Arabinofuranosyl-2-fluoroadenine; 2-Fluoroadenine-9-bata-D-arabinofuranoside

Formula Structure:

Molecular Formula :

C10H12FN5O4

Molecular Weight:

285. 23

CAS #:

21679-14-1

EINECS #:

244-525-5
Physical and Chemical
Properties: Fludarabine(21679-14-1)
   Melting Point  260℃.
insoluble in water and organic solvent.
Other Information
Product Application: Use of Fludarabine(21679-14-1)
   Its phosphoric acid group in the blood is rapidly split, the remaining 2 - fluoroethyl vidarabine (Fara-A) into the cell, and is phosphorylated to become Farar-ATP with the activity of metabolites and play a role for chroniclymphoblastic leukemia.
Others: 1. Functions an Features
    Fludarabine is a fluorinated nucleotide derivatives vidarabine, some pharmacological effects similar to cytarabine. The vidarabine soon Adenosine deaminase role and inactivation, while the product wasthis enzyme inactivated after oral administration, plus phosphorylation of the active metabolite 2 - fluoro - vidarabine triphosphate can inhibit DNA synthesis.
2. Attending Functions
   Fludarabine for B-cell chronic lymphocytic leukemia (CLL) a significant effect, especially effective in patients with failure of conventional treatment programs.
3. Storage
   Avoiding meeting up , hermetic, refrigeration preserves.

 

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